User Feedback :: Pendrive as a disk
Of course you can backup to a pendrive. This discussion is bordering on ridiculous.
Now say you have 10,000 writes to a pendrive and you backup twice each day, so we have 5,000/365 or about 13 years of use. YMMV
Running a flash device like a hard drive is totally different.
The number of writes occuring while running an os is huge compared to the single write session during backup of user data files. And with the write once of the saved apps also is much kinder to flash. The difference of backup and mydsl app saving is explained in the Getting Started document and the wiki. If you use dsl apps from the mydsl system it is trivial to save them via a write once to whatever writeable persistent storage device you choose. If you are expecting DSL to make all the decsions for you then I would suggest to look elsewhere. DSL is certainly not a demo system.
original here.