USB booting :: USB pen drive and USB hard drive, problem?

I think I figured out one thing I'll be doing with the Mini-ITX boards I bought. I want to put all my CDs on a drive and do the network jukebox thing. I don't want to stream to the Internet, just use them on my network. But I got to thinking about the setup. I would probably have a USB hard drive to store all the music. If I'm booting off a USB pen, will this cause issues when it finds the USB hard drive? Would I be better off installing to a small partition on the hard drive instead of using the pen drive? Thanks

F_M

No, there should be no problem in doing that - both ways should be fine.

original here.